???????????? ??????????????? ?????, 13.9% ???????? ?????? ????? ??? ????? ????????? ???? ???????????? ??????????????? ???? ???????? ?????????? ??????? ???? ??? ??? ?????? ????? ?????? ??????? ??? ??????? ????? ????? ?? ????????????? ??????? ???????? ????? ????? Dosage & Administration: .Adults: Apply a thin layer of Eflornithine cream, 13.9% to affected areas of the face and adjacent involved areas under the chin and rub in thoroughly. Do not wash the treated area for at least 4 hours. Use twice daily at least 8 hours apart or as directed by a physician. The patient should continue to use hair removal techniques as needed in conjunction with Eflornithine (Wonica should be applied at least 5 minutes after hair removal). Cosmetics or sunscreens may be applied over treated areas after the cream has dried. .Elderly: No apparent differences in safety were observed between older patients and younger patients. .Children: The safety and effectiveness of this product have not been established in pediatric patients less than 12 years of age. Side Effects .Adverse events were primarily mild in intensity and generally resolved without medical treatment or discontinuation of Eflornithine. Side effects can include acne, barbie, pseudofolliculitis, stinging skin, headache, burning skin, dry skin, erythema (redness), pruritus (itching), tingling skin, dyspepsia, skin irritation, rash, alopecia, dizziness, folliculitis, hair ingrown, facial edema, anorexia, nausea, asthenia, vertigo