Indications Alfacalcidol is indicated in: It is used to increase the amount of vitamin D in your body. This often increases calcium levels as well which can help in treatment of certain illnesses. In general this drug is used to treat diseases where the amount of calcium and phosphate (which is controlled by the level of vitamin D) in your body needs changing. Benefits of being on this drug can include control of the levels of calcium and phosphate in your body. Treat and prevent bone conditions that are caused by kidney failure (osteodystrophy) Treat illnesses and abnormalities affecting the parathyroid glands which make a substance called the parathyroid hormone. Correct low levels of calcium in the blood of newborn babies (hypocalcaemia) Treat the softening and deformity of the bones due to lack of calcium (rickets or osteomalacia)