Acerux is an antiviral medicine which helps in treating skin infections caused by Herpes simplex virus such as herpes labialis. It prevents the multiplication of the virus in skin cells and therefore helps in clearing the skin infection. Acerux is for external use only. You should use it in the dose and duration as advised by your doctor. The affected area should be clean and dry before application of the ointment. You must wash your hands thoroughly before and after applying this medicine. Do not touch the sores unnecessarily with your hands or towel, to avoid spreading the infection. Some common side effects include burning, irritation, itching and redness of the skin, at the site of application. Please consult your doctor if these side effects persist for a longer duration. Do not use it in the eyes, mouth, nose or vagina as it may cause irritation. If accidental exposure occurs, rinse immediately with plenty of water.

Uses of Acerux

• Herpes labialis

Side effects of Acerux

• Application site reactions (burning, irritation, itching and redness)

How to use Acerux

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Acerux works

Acerux is an antiviral medication which treats skin infections caused by Herpes simplex virus. It works by preventing the multiplication of virus in the skin cells. This stops the virus from producing new viruses and clears up your skin infection.

What if you forget to take Acerux?

If you miss a dose of Acerux, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Indication

As 5% oint/cream: Apply to the affected skin 5-6 times/day for 5-10 days.

Administration

Probenecid, cimetidine and mycophenolate mofetil may increase the plasma concentration of aciclovir. Increased nephrotoxic effects w/ drugs that affect renal physiology (e.g. ciclosporin, tacrolimus).

Adult Dose

Renal impairment. Pregnancy, lactation. Neurological abnormalities with significant hypoxia, serious hepatic or electrolyte abnormalities. Maintain adequate hydration. Lactation: Excretion in milk unknown; systemic exposure is minimal after topical application.

Renal Dose

Activity against HSV types I and II and varicella-zoster virus is due to intracellular conversion of aciclovir to the monophosphate by viral thymidine kinase with subsequent conversion to the diphosphate and active triphosphate by cellular enzymes. This active form inhibits viral DNA synthesis and replication by interfering with viral DNA polymerase enzyme and being incorporated into viral DNA.

Precaution

Herpes virus infections of skin

Pregnancy Category Note

>10% Burning/stinging (30%) 1-10% Pruritus (4%) <1% Dry lips (<1%),Rash (0.3%) Frequency Not Defined Angioedema,Vulvitis

Interaction

Hypersensitivity.